Although similar to ICSI, Intracytoplasmic morphologically selected sperm injection or IMSI, is a much more enhanced procedure, aimed at selecting superior quality sperm for fertilisation. The IMSI procedure, an effective method to overcome male infertility, was developed for decreasing the failure rate in artificial fertilisation by selecting morphologically advanced sperms from male semen for fertilisation.
Once the sperm is selected, it is used to fertilise an egg by procedures similar to ICSI. This includes holding the egg in a pipette while the sperm is injected directly into the cytoplasm of the egg. While the sperm is magnified 200 times for detecting any defects in its morphology, IMSI procedure magnifies it to about 7000 times.
Who Can Benefit From IMSI?
Intracytoplasmic Morphologically Selected Sperm Injection is best suited for the following candidates
- Men above the age of 40 years
- Patients who have a high count of abnormal sperm
- Patients facing a shortage of superior quality embryos
- Couples facing previous history of miscarriages
- Patients with a history of failed treatment cycles
The magnification procedures involved in IMSI involves detection of morphological defects such as chromatin compaction defects and intra nuclear sperm defects, which are hard to detect with simpler methods of ICSI.
The procedure for IMSI involves collection of sperm and ovum from the couple during extraction techniques depending on the fertility conditions of the partners. The sperm is then analysed under a high-powered microscope and magnified to about 7000 times to detect irregularities.
A morphologically robust and good quality sperm is injected into the collected ovum through procedures similar to that of ICSI. The embryo, after fertilisation period ranging from 3 to 6 days, is implanted in the womb for conception of pregnancy.
Benefits Of IMSI
The benefits of IMSI are as follows: -
- Ensures a high rate of successful pregnancy
- Prevents miscarriages to a substantial extent
- Helps in creation of superior quality embryo
With an advanced infrastructure, latest treatment options and skilled experts, GFRC (Genesis Fertility Research Centre), offers treatment for all infertility disorders.
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